Background: Posterior reversible encephalopathy syndrome (PRES) is a rare clinical-radiological syndrome characterized by such symptoms as headaches, altered consciousness, blurred vision, seizure, and focal neurological deficits.We Coasters herein present well-documented PRES cases and discuss the risk factors and characteristic imaging patterns o
A numerical and experimental investigation in to the role of gasoline surrogates and their reduced chemical kinetic mechanisms in spark ignition (SI) engine knocking has been carried out.In order to predict autoignition of gasoline in a spark ignition engine three reduced chemical kinetic mechanisms have been coupled with quasi-dimensional thermody
CYP-dependent metabolites play a critical role in regulating the cell cycle, as well as the proliferative, invasive, and migratory activity of cancer cells.We conducted a study to analyze the relative gene expression of various CYPs (CYP7B1, CYP27A1, CYP39A1, CYP51, CYP1B1, CYP3A5, CYP4F8, CYP5A1, CYP4F2, CYP2J2, CYP2E1, CYP2R1, CYP27B1, CYP24A1) i
Introduction Diabetes mellitus (DM) is increasingly recognized as a possible consequence of statin therapy.Secondary analysis of randomized clinical trials and limited observational cohort analyses Lecterns have suggested that women may be more likely than men to experience statin-associated DM.No analyses of real-world drug safety data addressing
Recessive dystrophic epidermolysis bullosa is a severe skin fragility disease caused by loss of functional type VII collagen at the dermal-epidermal junction.A frameshift mutation in exon 80 of COL7A1 gene, c.6527insC, is highly prevalent in the Spanish patient population.We have implemented gene-editing strategies for COL7A1 frame restoration Ligh